Typically, if you are clicking the "Create Item" button and nothing seems to be happening, it's because you have left a field or section unfilled or incomplete. Scroll up to see if there are any error messages and correct those fields or sections.
Remember, every item must be associated with a donor. The donor cannot be a company only, it must be associated with an email address/user account.
If you click "Create Item + Continue" you may be saving the item but it will stay on this page. Continue means that you have more to do after you save, such as adding images.